| Title | Connecting Cryptococcal Meningitis and Gut Microbiome |
| Author | |
| Corresponding Author | Zhao, Xinyuan; Xue, Peng |
| Publication Years | 2023-09-01
|
| DOI | |
| Source Title | |
| ISSN | 1661-6596
|
| EISSN | 1422-0067
|
| Volume | 24Issue:17 |
| Abstract | Fungal pathogens of the Cryptococcus neoformans species complex (C. neoformans SC) are a major cause of fungal meningitis in immunocompromised individuals. As with other melanotic microorganisms associated with human diseases, the cell-wall-associated melanin of C. neoformans SC is a major virulence factor that contributes to its ability to evade host immune responses. The levels of melanin substrate and the regulation of melanin formation could be influenced by the microbiota-gut-brain axis. Moreover, recent studies show that C. neoformans infections cause dysbiosis in the human gut microbiome. In this review, we discuss the potential association between cryptococcal meningitis and the gut microbiome. Additionally, the significant potential of targeting the gut microbiome in the diagnosis and treatment of this debilitating disease is emphasized. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Others
|
| Funding Project | National Natural Science Foundation of China[82173554]
; Natural Science Foundation of Jiangsu Province[BK20201444]
; Nantong University student innovation training program project[202310304049Z]
|
| WOS Research Area | Biochemistry & Molecular Biology
; Chemistry
|
| WOS Subject | Biochemistry & Molecular Biology
; Chemistry, Multidisciplinary
|
| WOS Accession No | WOS:001061225500001
|
| Publisher | |
| ESI Research Field | CHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:0
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/559318 |
| Department | School of Medicine |
| Affiliation | 1.Nantong Univ, Sch Publ Hlth, Dept Occupat Med & Environm Toxicol, Nantong Key Lab Environm Toxicol, Nantong 226019, Peoples R China 2.Southern Univ Sci & Technol, Sch Med, Shenzhen 518055, Peoples R China |
| Recommended Citation GB/T 7714 |
Ma, Yuanyuan,Yang, Liang,Jiang, Mengna,et al. Connecting Cryptococcal Meningitis and Gut Microbiome[J]. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,2023,24(17).
|
| APA |
Ma, Yuanyuan,Yang, Liang,Jiang, Mengna,Zhao, Xinyuan,&Xue, Peng.(2023).Connecting Cryptococcal Meningitis and Gut Microbiome.INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES,24(17).
|
| MLA |
Ma, Yuanyuan,et al."Connecting Cryptococcal Meningitis and Gut Microbiome".INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 24.17(2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
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