中文版 | English
Title

Bioactive and Biodegradable Polycaprolactone-Based Nanocomposite for Bone Repair Applications

Author
Corresponding AuthorEmadi, Hosein; Khayatzadeh, Saber; Lotfian, Saeid
Publication Years
2023-09-01
DOI
Source Title
EISSN
2073-4360
Volume15Issue:17
Abstract
This study investigated the relationship between the structure and mechanical properties of polycaprolactone (PCL) nanocomposites reinforced with baghdadite, a newly introduced bioactive agent. The baghdadite nanoparticles were synthesised using the sol-gel method and incorporated into PCL films using the solvent casting technique. The results showed that adding baghdadite to PCL improved the nanocomposites' tensile strength and elastic modulus, consistent with the results obtained from the prediction models of mechanical properties. The tensile strength increased from 16 to 21 MPa, and the elastic modulus enhanced from 149 to 194 MPa with fillers compared to test specimens without fillers. The thermal properties of the nanocomposites were also improved, with the degradation temperature increasing from 388 & DEG;C to 402 & DEG;C when 10% baghdadite was added to PCL. Furthermore, it was found that the nanocomposites containing baghdadite showed an apatite-like layer on their surfaces when exposed to simulated body solution (SBF) for 28 days, especially in the film containing 20% nanoparticles (PB20), which exhibited higher apatite density. The addition of baghdadite nanoparticles into pure PCL also improved the viability of MG63 cells, increasing the viability percentage on day five from 103 in PCL to 136 in PB20. Additionally, PB20 showed a favourable degradation rate in PBS solution, increasing mass loss from 2.63 to 4.08 per cent over four weeks. Overall, this study provides valuable insights into the structure-property relationships of biodegradable-bioactive nanocomposites, particularly those reinforced with new bioactive agents.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Others
WOS Research Area
Polymer Science
WOS Subject
Polymer Science
WOS Accession No
WOS:001061283500001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:0
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/559329
DepartmentDepartment of Mechanics and Aerospace Engineering
Affiliation
1.Univ Tehran, Coll Engn, Sch Mech Engn, Tehran 1417614411, Iran
2.Isfahan Univ Technol, Dept Mech Engn, Esfahan 8415683111, Iran
3.Isfahan Univ Technol, Dept Chem Engn, Esfahan 8415683111, Iran
4.Southern Univ Sci & Technol, Dept Mech & Aerosp Engn, Shenzhen Key Lab Soft Mech & Smart Mfg, Shenzhen 518055, Peoples R China
5.Isfahan Univ Technol, Dept Mat Engn, Esfahan 8415683111, Iran
6.Isfahan Univ Technol, Golpayegan Coll Engn, Mat Engn Grp, Esfahan 8415683111, Iran
7.Univ West England, Dept Engn Design & Math, Bristol BS16 1QY, England
8.Univ Strathclyde, Fac Engn, Glasgow G4 0LZ, Scotland
Recommended Citation
GB/T 7714
Emadi, Hosein,Karevan, Mehdi,Masoudi Rad, Maryam,et al. Bioactive and Biodegradable Polycaprolactone-Based Nanocomposite for Bone Repair Applications[J]. POLYMERS,2023,15(17).
APA
Emadi, Hosein.,Karevan, Mehdi.,Masoudi Rad, Maryam.,Sadeghzade, Sorour.,Pahlevanzadeh, Farnoosh.,...&Lotfian, Saeid.(2023).Bioactive and Biodegradable Polycaprolactone-Based Nanocomposite for Bone Repair Applications.POLYMERS,15(17).
MLA
Emadi, Hosein,et al."Bioactive and Biodegradable Polycaprolactone-Based Nanocomposite for Bone Repair Applications".POLYMERS 15.17(2023).
Files in This Item:
There are no files associated with this item.
Related Services
Fulltext link
Recommend this item
Bookmark
Usage statistics
Export to Endnote
Export to Excel
Export to Csv
Altmetrics Score
Google Scholar
Similar articles in Google Scholar
[Emadi, Hosein]'s Articles
[Karevan, Mehdi]'s Articles
[Masoudi Rad, Maryam]'s Articles
Baidu Scholar
Similar articles in Baidu Scholar
[Emadi, Hosein]'s Articles
[Karevan, Mehdi]'s Articles
[Masoudi Rad, Maryam]'s Articles
Bing Scholar
Similar articles in Bing Scholar
[Emadi, Hosein]'s Articles
[Karevan, Mehdi]'s Articles
[Masoudi Rad, Maryam]'s Articles
Terms of Use
No data!
Social Bookmark/Share
No comment.

Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.