| Title | Hydro Electroactive Janus Micro/Nano Fiber Dressing with Exudate Management Ability for Wound Healing |
| Author | |
| Corresponding Author | Chen, Weichao; Huang, Yuesheng; Li, Jiwei |
| Publication Years | 2023-09-01
|
| DOI | |
| Source Title | |
| ISSN | 2365-709X
|
| Abstract | ["Exudate management and bioelectric signals are critical to promoting wound healing. In this study, the thermoplastic polyurethane (TPU) nanofiber is directly electrospun on the cotton microfibers (Cotton) to prepare a Janus dressing (TPU/Cotton), which can unidirectionally drain the excess exudate. Then, Ag/Zn dot electrodes are deposited on the TPU layer, which can produce an electric field penetrating the wound when activated by wound exudate. The hydro-activated Ag/Zn's electrical stimulation (ES) can promote the migration of fibroblast cells and shows excellent antibacterial activity against E. coli and S. aureus. Furthermore, in vivo experiments show that the exudate management coupled with ES accelerated wound healing at multiple stages by promoting re-epithelization, collagen deposition, and vascularization. Moreover, the Ag/Zn@TPU/Cotton dressing shows excellent biocompatibility in the vitro cytotoxicity experiments. These findings may shed some light on developing the next generation of wound dressings with self-activated electrical stimulation and exudate management.","Ag/Zn dots are deposited on the thermoplastic polyurethane (TPU) layer of TPU/cotton nonwovens (Cotton). The hydro-activated Ag/Zn's electrical stimulation (ES) can promote the migration of fibroblast cells and show excellent antibacterial activity against E. coli and S. aureus. The exudate management coupled with ES can accelerate wound healing at multiple stages by promoting re-epithelization, collagen deposition, and vascularization.image"] |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Corresponding
|
| Funding Project | This work was partially supported by the National Natural Science Foundation of China (52203060), the State Key Development Program for Basic Research of China (2017YFC1103302), the Shandong Provincial Universities Youth Innovation Technology Plan Innovati[2017YFC1103302]
; National Natural Science Foundation of China[2022KJ152]
; State Key Development Program for Basic Research of China[2022M711735]
; null[52203060]
|
| WOS Research Area | Materials Science
|
| WOS Subject | Materials Science, Multidisciplinary
|
| WOS Accession No | WOS:001058882200001
|
| Publisher | |
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:1
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/559332 |
| Department | School of Medicine 南方科技大学医院 |
| Affiliation | 1.Qingdao Univ, Ind Res Inst Nonwovens & Tech Text, Coll Text & Clothing, Sch Basic Med, Qingdao 266071, Peoples R China 2.Southern Univ Sci & Technol, Southern Univ Sci & Technol Hosp, Inst Wound Repair & Regenerat Med, Sch Med,Dept Wound Repair, Shenzhen 518055, Peoples R China |
| Corresponding Author Affilication | School of Medicine; Southern University of Science and Technology Hospital |
| Recommended Citation GB/T 7714 |
Li, Ling,Zhao, Qian,Feng, Fan,et al. Hydro Electroactive Janus Micro/Nano Fiber Dressing with Exudate Management Ability for Wound Healing[J]. ADVANCED MATERIALS TECHNOLOGIES,2023.
|
| APA |
Li, Ling.,Zhao, Qian.,Feng, Fan.,Li, Chenglin.,Wang, Tiantian.,...&Li, Jiwei.(2023).Hydro Electroactive Janus Micro/Nano Fiber Dressing with Exudate Management Ability for Wound Healing.ADVANCED MATERIALS TECHNOLOGIES.
|
| MLA |
Li, Ling,et al."Hydro Electroactive Janus Micro/Nano Fiber Dressing with Exudate Management Ability for Wound Healing".ADVANCED MATERIALS TECHNOLOGIES (2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.
; 
Edit Comment