Dual-excitation carbon dots-based lateral flow visual sensing device for ratiometric determination and discrimination of tetracyclines in food

Guo，Guoqiang1; Li，Tingting1; Zheng，Qi1; Tang，Siyuan1,2; Hu，Houwen1; Wang，Xu1; Chen，Da1

2023-11-15

10.1016/j.snb.2023.134523

Sensors and Actuators B: Chemical   Impact Factor & Quartile

0925-4005

0925-4005

Excessive releasing of tetracyclines in the nature has constituted a major threat to ecosystem. Therefore, it is crucial to develop an accurate and convenient on-site analysis device for tetracyclines. Herein, we construct a neoteric dual-excitation carbon dots (DE-CDs) through microwave radiation and establish an excitation-based ratiometric approach for quantitative tetracyclines determination. The ratio of different excitation intensities under the same emission wavelength changes linearly in response to tetracyclines concentration. As a proof of feasibility, we choose doxycycline (DOX) as the analysis model. It shows a low detection limit (LOD) of 61 nM in a wide concentration range of 0.061–80 µM, suggesting that this sensor is conducive to application potential in tetracyclines determination of food products. Moreover, considering the differentiated overlap between tetracyclines absorbance and DE-CDs excitations, the discrimination of tetracyclines is realized in the form of mixtures. Significantly, combining with the DE-CDs, RGB (Red, Green and Blue) analysis and 3D printing technologies, we construct a miniaturized visual sensing device with low LOD and achieve the discrimination of TCs based on RGB variations, showing a great opportunity for industrial production of pollutant monitoring sensors in resource-constrained areas.

3D printing technology Dual-excitation carbon dots Excitation-based ratiometric sensing On-site quantitation and discrimination Tetracyclines

SCI

English

Others

National Natural Science Foundation of China[61604084];

Chemistry ; Electrochemistry ; Instruments & Instrumentation

Chemistry, Analytical ; Electrochemistry ; Instruments & Instrumentation

WOS:001073698200001

ELSEVIER SCIENCE SA

CHEMISTRY

2-s2.0-85169010839

Scopus

1.Department of Microelectronic Science and Engineering,School of Physical Science and Technology,Ningbo University,Ningbo,315211,China
2.Department of Materials Science and Engineering,Shenzhen Key Laboratory of Full Spectral Solar Electricity Generation (FSSEG),Southern University of Science and Technology,Shenzhen,518055,China

Guo，Guoqiang,Li，Tingting,Zheng，Qi,et al. Dual-excitation carbon dots-based lateral flow visual sensing device for ratiometric determination and discrimination of tetracyclines in food[J]. Sensors and Actuators B: Chemical,2023,395.

Guo，Guoqiang.,Li，Tingting.,Zheng，Qi.,Tang，Siyuan.,Hu，Houwen.,...&Chen，Da.(2023).Dual-excitation carbon dots-based lateral flow visual sensing device for ratiometric determination and discrimination of tetracyclines in food.Sensors and Actuators B: Chemical,395.

Guo，Guoqiang,et al."Dual-excitation carbon dots-based lateral flow visual sensing device for ratiometric determination and discrimination of tetracyclines in food".Sensors and Actuators B: Chemical 395(2023).