Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet

Hu，Ruoyang1,14; Li，Xuedong1; Hu，Yong1; Zhang，Runjie1; Lv，Qiang1; Zhang，Min1; Sheng，Xianyong1; Zhao，Feng1; Chen，Zhijia1; Ding，Yuhan1; Yuan，Huan1; Wu，Xiaofeng1; Xing，Shuang1; Yan，Xiaoyu1; Bao，Fang1; Wan，Ping1; Xiao，Lihong1,19; Wang，Xiaoqin1; Xiao，Wei1; Decker，Eva L.2; van Gessel，Nico2; Renault，Hugues2,20; Wiedemann，Gertrud2,21; Horst，Nelly A.2,22; Haas，Fabian B.3; Wilhelmsson，Per K.I.3; Ullrich，Kristian K.3,31; Neumann，Eva3; Lv，Bin4,23; Liang，Chengzhi5,32; Du，Huilong5,24; Lu，Hongwei5,25; Gao，Qiang5,8; Cheng，Zhukuan5,26; You，Hanli5,26; Xin，Peiyong5; Chu，Jinfang5,32; Huang，Chien Hsun6,33; Liu，Yang7,27,28; Dong，Shanshan27; Zhang，Liangsheng8; Chen，Fei9; Deng，Lei10; Duan，Fuzhou10; Zhao，Wenji10; Li，Kai11; Li，Zhongfeng11; Li，Xingru11; Cui，Hengjian12; Zhang，Yong E.13; Ma，Chuan14; Zhu，Ruiliang15; Jia，Yu16; Wang，Meizhi16; Hasebe，Mitsuyasu17,34; Fu，Jinzhong4; Goffinet，Bernard7; Ma，Hong18; Rensing，Stefan A.3,29; Reski，Ralf2,30; He，Yikun1

2023-08-17

10.1016/j.cell.2023.07.003

Cell   Impact Factor & Quartile

0092-8674

1097-4172

The most extreme environments are the most vulnerable to transformation under a rapidly changing climate. These ecosystems harbor some of the most specialized species, which will likely suffer the highest extinction rates. We document the steepest temperature increase (2010–2021) on record at altitudes of above 4,000 m, triggering a decline of the relictual and highly adapted moss Takakia lepidozioides. Its de-novo-sequenced genome with 27,467 protein-coding genes includes distinct adaptations to abiotic stresses and comprises the largest number of fast-evolving genes under positive selection. The uplift of the study site in the last 65 million years has resulted in life-threatening UV-B radiation and drastically reduced temperatures, and we detected several of the molecular adaptations of Takakia to these environmental changes. Surprisingly, specific morphological features likely occurred earlier than 165 mya in much warmer environments. Following nearly 400 million years of evolution and resilience, this species is now facing extinction.

abiotic stress adaptive evolution development DNA repair fast-evolving genome gene expansion global warming molecular clock paleontology UV radiation

English

NI Journal Papers

Others

National Natural Science Foundation of China[31970658];National Natural Science Foundation of China[91631109];

MOLECULAR BIOLOGY & GENETICS

2-s2.0-85167827135

Scopus

1.Beijing Key Laboratory of Plant Gene Resources and Biotechnology for Carbon Reduction and Environmental Improvement,College of Life Sciences,Capital Normal University (CNU),Beijing,100048,China
2.Plant Biotechnology,Faculty of Biology,University of Freiburg,Freiburg,79104,Germany
3.Department of Biology,University of Marburg,Marburg,35043,Germany
4.Department of Integrative Biology,University of Guelph,Guelph,N1G 2W1,Canada
5.National Centre for Plant Gene Research (Beijing),Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing,100101,China
6.State Key Laboratory of Genetic Engineering and Collaborative Innovation Center of Genetics and Development,Ministry of Education Key Laboratory of Biodiversity and Ecological Engineering,School of Life Sciences,Fudan University,Shanghai,200433,China
7.Department of Ecology and Evolutionary Biology,University of Connecticut,Storrs,Unit 3043,06269,United States
8.Genomics and Genetic Engineering Laboratory of Ornamental Plants,College of Agriculture and Biotechnology,Zhejiang University,Hangzhou,Zhejiang,310058,China
9.Sanya Nanfan Research Institute from Hainan University,Hainan Yazhou Bay Seed Laboratory,Sanya,Hainan,572025,China
10.College of Resource Environment and Tourism,CNU,Beijing,100048,China
11.Department of Chemistry,CNU,Beijing,100048,China
12.School of Mathematical Sciences,CNU,Beijing,100048,China
13.Key Laboratory of Zoological Systematics and Evolution,Institute of Zoology,Chinese Academy of Sciences,Beijing,100101,China
14.State Key Laboratory of Resource Insects,Institute of Apicultural Research,Chinese Academy of Agricultural Sciences,Beijing,100193,China
15.Department of Biology,School of Life Sciences,East China Normal University,Shanghai,200241,China
16.State Key Laboratory of Systematic and Evolutionary Botany,Institute of Botany,Chinese Academy of Sciences,Beijing,100093,China
17.Division of Evolutionary Biology,National Institute for Basic Biology,Okazaki,Aichi,444-8585,Japan
18.Department of Biology,Huck Institutes of the Life Sciences,Pennsylvania State University,University Park,16802,United States
19.State Key Laboratory of Subtropical Silviculture,Zhejiang A&F University,Hangzhou,Zhejiang,311300,China
20.Institut de Biologie Moléculaire des Plantes (IBMP),CNRS,University of Strasbourg,Strasbourg,67084,France
21.Inselspital,University of Bern,Bern,3010,Switzerland
22.MetaSystems Hard & Software GmbH,Altlussheim,68804,Germany
23.Chengdu Institute of Biology,Chinese Academy of Sciences,Chengdu,Sichuan,610041,China
24.School of Life Sciences,Institute of Life Sciences and Green Development,Hebei University,Baoding,Hebei,071002,China
25.Department of Biology,School of Life Sciences,Southern University of Science and Technology,Shenzhen,Guangdong,518055,China
26.Key Laboratory of Plant Functional Genomics of the Ministry of Education,Jiangsu Co-Innovation Center for Modern Production Technology of Grain Crops,Yangzhou University,Yangzhou,Jiangsu,225009,China
27.Key Laboratory of Southern Subtropical Plant Diversity,Fairy Lake Botanical Garden,Shenzhen & Chinese Academy of Sciences,Shenzhen,Guangdong,518004,China
28.State Key Laboratory of Agricultural Genomics,BGI-Shenzhen,Shenzhen,Guangdong,518085,China
29.Faculty of Chemistry and Pharmacy,University of Freiburg,Freiburg,79104,Germany
30.Signalling Research Centres BIOSS and CIBSS,University of Freiburg,Freiburg,79104,Germany
31.Department of Evolutionary Genetics,Max Planck Institute for Evolutionary Biology,Plön,24306,Germany
32.University of Chinese Academy of Sciences,Beijing,100049,China
33.Key Laboratory of Forage and Endemic Crop Biology,Ministry of Education,School of Life Sciences,Inner Mongolia University,Hohhot,010031,China
34.Department of Basic Biology,The Graduate School for Advanced Studies (SOKENDAI),Okazaki,444-8585,Japan

Hu，Ruoyang,Li，Xuedong,Hu，Yong,et al. Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet[J]. Cell,2023,186(17):3558-3576.e17.

Hu，Ruoyang.,Li，Xuedong.,Hu，Yong.,Zhang，Runjie.,Lv，Qiang.,...&He，Yikun.(2023).Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet.Cell,186(17),3558-3576.e17.

Hu，Ruoyang,et al."Adaptive evolution of the enigmatic Takakia now facing climate change in Tibet".Cell 186.17(2023):3558-3576.e17.