Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems
|Corresponding Author||Li，Pengfei; Li，Wenjun|
Conjugate addition is one of the most powerful and practical methods for the formation of carbon-carbon and carbon-heteroatom bonds in organic synthesis. Owing to the rapid development of asymmetric catalysis, significant progress has been made in the field of asymmetric conjugate addition, such as 1,4-addition and 1,6-addition. However, formidable challenge of controlling chemo-, regio- and stereoselectivity arises with the extended conjugated systems. Recently, with the aid of Brønsted acids catalysis, functionalized benzyl alcohols and indolylmethanols has been successfully developed as suitable precursors of electron-deficient conjugate systems for organocatalytic remote stereocontrolled conjugate additions. This review investigates the advances in the field of organocatalytic enantioselective 1,8-conjugate addition and 1,10-conjugate addition of in situ formed electron-deficient conjugate systems from functionalized alcohols, which is organized according to the substrates.
Natural Science Foundation of Shandong Province[ZR2021MB026];
|WOS Research Area|
Chemistry, Applied ; Chemistry, Organic
|WOS Accession No|
Cited Times [WOS]:0
|Document Type||Journal Article|
|Department||Department of Chemistry|
1.Department of Medicinal Chemistry,School of Pharmacy,Qingdao University,Qingdao,308 Ningxia Road, Shandong,266021,China
2.Shenzhen Grubbs Institute and Department of Chemistry,Southern University of Science and Technology Guangming Advanced Research Institute,College of Science,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Blvd., Guangdong, Nanshan District,518055,China
|Corresponding Author Affilication||Department of Chemistry; Shenzhen Grubbs Institute; College of Science|
Yue，Zhibin,Fang，Fang,Xia，Yan,et al. Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems[J]. Advanced Synthesis and Catalysis,2023,365(12):1926-1933.
Yue，Zhibin,Fang，Fang,Xia，Yan,Li，Pengfei,&Li，Wenjun.(2023).Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems.Advanced Synthesis and Catalysis,365(12),1926-1933.
Yue，Zhibin,et al."Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems".Advanced Synthesis and Catalysis 365.12(2023):1926-1933.
|Files in This Item:||There are no files associated with this item.|
|Recommend this item|
|Export to Endnote|
|Export to Excel|
|Export to Csv|
|Similar articles in Google Scholar|
|Similar articles in Baidu Scholar|
|Similar articles in Bing Scholar|
Items in the repository are protected by copyright, with all rights reserved, unless otherwise indicated.