中文版 | English
Title

Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems

Author
Corresponding AuthorLi,Pengfei; Li,Wenjun
Publication Years
2023-06-20
DOI
Source Title
ISSN
1615-4150
EISSN
1615-4169
Volume365Issue:12Pages:1926-1933
Abstract
Conjugate addition is one of the most powerful and practical methods for the formation of carbon-carbon and carbon-heteroatom bonds in organic synthesis. Owing to the rapid development of asymmetric catalysis, significant progress has been made in the field of asymmetric conjugate addition, such as 1,4-addition and 1,6-addition. However, formidable challenge of controlling chemo-, regio- and stereoselectivity arises with the extended conjugated systems. Recently, with the aid of Brønsted acids catalysis, functionalized benzyl alcohols and indolylmethanols has been successfully developed as suitable precursors of electron-deficient conjugate systems for organocatalytic remote stereocontrolled conjugate additions. This review investigates the advances in the field of organocatalytic enantioselective 1,8-conjugate addition and 1,10-conjugate addition of in situ formed electron-deficient conjugate systems from functionalized alcohols, which is organized according to the substrates.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
Corresponding
Funding Project
Natural Science Foundation of Shandong Province[ZR2021MB026];
WOS Research Area
Chemistry
WOS Subject
Chemistry, Applied ; Chemistry, Organic
WOS Accession No
WOS:000998682900001
Publisher
Scopus EID
2-s2.0-85160736428
Data Source
Scopus
Citation statistics
Cited Times [WOS]:0
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/559927
DepartmentDepartment of Chemistry
理学院
深圳格拉布斯研究院
Affiliation
1.Department of Medicinal Chemistry,School of Pharmacy,Qingdao University,Qingdao,308 Ningxia Road, Shandong,266021,China
2.Shenzhen Grubbs Institute and Department of Chemistry,Southern University of Science and Technology Guangming Advanced Research Institute,College of Science,Southern University of Science and Technology,Shenzhen,1088 Xueyuan Blvd., Guangdong, Nanshan District,518055,China
Corresponding Author AffilicationDepartment of Chemistry;  Shenzhen Grubbs Institute;  College of Science
Recommended Citation
GB/T 7714
Yue,Zhibin,Fang,Fang,Xia,Yan,et al. Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems[J]. Advanced Synthesis and Catalysis,2023,365(12):1926-1933.
APA
Yue,Zhibin,Fang,Fang,Xia,Yan,Li,Pengfei,&Li,Wenjun.(2023).Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems.Advanced Synthesis and Catalysis,365(12),1926-1933.
MLA
Yue,Zhibin,et al."Organocatalytic Remote Stereocontrolled Additions of In Situ Formed Electron-Deficient Conjugate Systems".Advanced Synthesis and Catalysis 365.12(2023):1926-1933.
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