Mechanically-Compliant Bioelectronic Interfaces through Fatigue-Resistant Conducting Polymer Hydrogel Coating

Xue，Yu1; Chen，Xingmei1; Wang，Fucheng1; Lin，Jingsen1; Liu，Ji1,2,3,4

2023

10.1002/adma.202304095

Advanced Materials   Impact Factor & Quartile

0935-9648

1521-4095

Because of their distinct electrochemical and mechanical properties, conducting polymer hydrogels have been widely exploited as soft, wet, and conducting coatings for conventional metallic electrodes, providing mechanically compliant interfaces and mitigating foreign body responses. However, the long-term viability of these hydrogel coatings is hindered by concerns regarding fatigue crack propagation and/or delamination caused by repetitive volumetric expansion/shrinkage during long-term electrical interfacing. This study reports a general yet reliable approach to achieving a fatigue-resistant conducting polymer hydrogel coating on conventional metallic bioelectrodes by engineering nanocrystalline domains at the interface between the hydrogel and metallic substrates. It demonstrates the efficacy of this robust, biocompatible, and fatigue-resistant conducting hydrogel coating in cardiac pacing, showcasing its ability to effectively reduce the pacing threshold voltage and enhance the long-term reliability of electric stimulation. This study findings highlight the potential of its approach as a promising design and fabrication strategy for the next generation of seamless bioelectronic interfaces.

bioelectrodes biointerfaces fatigue-resistant hydrogel coating mechanical compliance

SCI

English

NI Journal Papers ; NI论文

First ; Corresponding

National Science and Technology Innovation[2022ZD0209500] ; Natural Science Foundation of Guangdong Province[2022A1515010152] ; Basic Research Program of Shenzhen["JCYJ20210324105211032","GJHZ20210705141809030"] ; Scientific Research Platforms and Projects of University of Guangdong Provincial Education Office[2022ZDZX3019] ; Science, Technology and Innovation Commission of Shenzhen Municipality["ZDSYS20200811143601004","ZDSYS20220527171403009"]

Chemistry ; Science & Technology - Other Topics ; Materials Science ; Physics

Chemistry, Multidisciplinary ; Chemistry, Physical ; Nanoscience & Nanotechnology ; Materials Science, Multidisciplinary ; Physics, Applied ; Physics, Condensed Matter

WOS:001041325200001

WILEY-V C H VERLAG GMBH

MATERIALS SCIENCE

2-s2.0-85166281193

Scopus

1.Department of Mechanical and Energy Engineering,Southern University of Science and Technology,Shenzhen,518055,China
2.Shenzhen Key Laboratory of Biomimetic Robotics and Intelligent Systems,Department of Mechanical and Energy Engineering,Southern University of Science and Technology,Shenzhen,518055,China
3.Shenzhen Key Laboratory of Intelligent Robotics and Flexible Manufacturing Systems,Southern University of Science and Technology,Shenzhen,518055,China
4.Guangdong Provincial Key Laboratory of Human-Augmentation and Rehabilitation Robotics in Universities,Southern University of Science and Technology,Shenzhen,518055,China

Xue，Yu,Chen，Xingmei,Wang，Fucheng,et al. Mechanically-Compliant Bioelectronic Interfaces through Fatigue-Resistant Conducting Polymer Hydrogel Coating[J]. Advanced Materials,2023,35(40).

Xue，Yu,Chen，Xingmei,Wang，Fucheng,Lin，Jingsen,&Liu，Ji.(2023).Mechanically-Compliant Bioelectronic Interfaces through Fatigue-Resistant Conducting Polymer Hydrogel Coating.Advanced Materials,35(40).

Xue，Yu,et al."Mechanically-Compliant Bioelectronic Interfaces through Fatigue-Resistant Conducting Polymer Hydrogel Coating".Advanced Materials 35.40(2023).