The potential role of minimal/molecular residual disease in colorectal cancer: Curative surgery, radiotherapy and beyond
Detection of minimal/molecular residual disease (MRD) based on ctDNA assay develops from hematological malignancies to solid tumors. Generally, there are two mainstream assays in MRD testing technology: tumor-informed and tumor-agnostic. For colorectal cancer (CRC), MRD is used not only to monitor recurrence and predict prognosis, but also to help in clinical decision making and assessment of clinical efficacy in the settings of curative surgery, radiotherapy, chemotherapy and surveillance. Accumulated clinical trials are exploring roles of MRD in early or advanced stages of CRC. Here, we give an overview of how MRD is and will be used in CRC.
Science, Technology and Innovation Commission of Shenzhen Municipality[JCYJ20190807150403655] ; Shenzhen Graduate School, Peking University[SYWGSLCYJ202202]
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Cited Times [WOS]:0
|Document Type||Journal Article|
|Department||Shenzhen People's Hospital|
1.Department of Oncology,Shenzhen People's Hospital (the Second Clinical Medical College,Jinan University; the First Affiliated Hospital,Southern University of Science and Technology),Shenzhen,China
2.Department of Biology,School of Medicine,Southern University of Science and Technology,Shenzhen,China
3.Department of Colorectal Surgery,State Key Laboratory of Oncology in South China,Collaborative Innovation Center for Cancer Medicine,Sun Yat-Sen University Cancer Center,Guangzhou,China
|First Author Affilication||Shenzhen People's Hospital|
|First Author's First Affilication||Shenzhen People's Hospital|
Xu，Meiyi,Shi，Tianhao,Xu，Ruilian,et al. The potential role of minimal/molecular residual disease in colorectal cancer: Curative surgery, radiotherapy and beyond[J]. Journal of the National Cancer Center,2023,3(3).
Xu，Meiyi,Shi，Tianhao,Xu，Ruilian,Chen，Gong,&He，Wan.(2023).The potential role of minimal/molecular residual disease in colorectal cancer: Curative surgery, radiotherapy and beyond.Journal of the National Cancer Center,3(3).
Xu，Meiyi,et al."The potential role of minimal/molecular residual disease in colorectal cancer: Curative surgery, radiotherapy and beyond".Journal of the National Cancer Center 3.3(2023).
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