Ir-Catalyzed B(3)-Amination of o-Carboranes with Amines via Acceptorless Dehydrogenative BH/NH Cross-Coupling

Ki Au, Yik1,2; Ma, Qiangqiang1,2; Zhang, Jie1,2; Xie, Zuowei1,2,3,4

2023-09-01

10.1002/asia.202300611

CHEMISTRY-AN ASIAN JOURNAL   Impact Factor & Quartile

1861-4728

1861-471X

An efficient and convenient strategy for Ir-catalyzed selective B(3)-amination of o-carboranes with amines via acceptorless BH/NH dehydrocoupling was developed, affording a series of B(3)-aminated-o-carboranes in moderate to high isolated yields with H2 gas as a sole by-product. Such an oxidant-free system endues the protocol sustainability, atom-economy and environmental friendliness. A reaction mechanism via an Ir(I)-Ir(III)-Ir(I) catalytic cycle involving oxidative addition, dehydrogenation and reductive elimination was proposed.

amination B-H activation carborane dehydrogenative cross-coupling regioselectivity

SCI

English

Corresponding

This work was supported by a grant from the Research Grants Council of HKSAR (Project No. 14305420).[14305420]

Chemistry

Chemistry, Multidisciplinary

WOS:001072972200001

WILEY-V C H VERLAG GMBH

Web of Science

1.Chinese Univ Hong Kong, Dept Chem, Shatin, Hong Kong, Peoples R China
2.Chinese Univ Hong Kong Shatin, State Key Lab Synthet Chem, Shatin, Hong Kong, Peoples R China
3.Southern Univ Sci & Technol, Shenzhen Grubbs Inst, Shenzhen 518055, Peoples R China
4.Southern Univ Sci & Technol, Dept Chem, Shenzhen 518055, Peoples R China

Ki Au, Yik,Ma, Qiangqiang,Zhang, Jie,et al. Ir-Catalyzed B(3)-Amination of o-Carboranes with Amines via Acceptorless Dehydrogenative BH/NH Cross-Coupling[J]. CHEMISTRY-AN ASIAN JOURNAL,2023.

Ki Au, Yik,Ma, Qiangqiang,Zhang, Jie,&Xie, Zuowei.(2023).Ir-Catalyzed B(3)-Amination of o-Carboranes with Amines via Acceptorless Dehydrogenative BH/NH Cross-Coupling.CHEMISTRY-AN ASIAN JOURNAL.

Ki Au, Yik,et al."Ir-Catalyzed B(3)-Amination of o-Carboranes with Amines via Acceptorless Dehydrogenative BH/NH Cross-Coupling".CHEMISTRY-AN ASIAN JOURNAL (2023).