Comparasion of the anatomic and therapeutic effect of two transsphenoidal approaches under neuroendoscopy

Wang, Hao3,4; Hao, Wenwen1; Peng, Yuping1; Qi, Songtao1; Shi, Jin1; Li, Gang2; Wang, Lu2; Fan, Jun1; Liu, Yi1; Du, Bo3; Li, Yu1

2023-12-01

10.1016/j.jrras.2023.100645

JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES   Impact Factor & Quartile

1687-8507

Objective: To compare anatomical parameters, postoperative nasal complications and quality of life of 2 sphenoid sinus approaches (nasal septum approach and transsphenoidal anterior wall approach) via anterior wall by endoscopic surgery. Methods: The study was anatomic basis research and prospective randomized double-blind (Clinical trials registration number: NFEC-2015-033). Study was performed in 30 dissected heads via 2 approaches. The related anatomic parameters were measured. Another 60 patients with pituitary tumor were randomly divided into 2 groups to receive endoscopic surgery. The selected otolaryngologist and non-operative neurosurgeon common then analyzed preoperative indicators. The therapeutic effect and nasal complications of 2 transsphenoidal approaches were compared by Lund-Kennedy scale, Lund-Mackay scale and SNOT-20 scale. Results: The distances between incision and external nostrils of anterior wall in nasal septum approach and transsphenoidal anterior wall approach are 5.19 & PLUSMN; 0.15 versus 6.91 & PLUSMN; 0.14 cm, respectively; maximum angles and ranges of swing in horizontal direction on operative route are 44.77 & PLUSMN; 2.04 degrees versus 38.54 & PLUSMN; 1.40 degrees, and 1.25 & PLUSMN; 0.15 versus 0.59 & PLUSMN; 0.52 cm. The operation time in nasal septum approach group is shorter (61.97 & PLUSMN; 18.123 min) than transsphenoidal anterior wall approach group (89.83 & PLUSMN; 38.515 min); And higher Lund-Kennedy score (2.4737 & PLUSMN; 1.46699 vs 3.8125 & PLUSMN; 1.51520. In addition, 20 Subjective Scoring Scales for Nasal and Paranasal Sinus Outcome (SNOT-20) measurement results indicated nasal septum approach group has less subjective symptoms plague patients' lives. The cerebrospinal fluid leakage, resection of tumor, postoperative endocrine remission rate and postoperative complications occurred in 2 groups have no significant difference. Conclusion: Endonasal transsphenoidal via nasal septum-sphenoid sinus approach has characters of less surgery damage, short distance to the outside of the nose, precise location, wider operation space and larger perspective, which is obvious advantages in reducing postoperative nasal complications.

Neuroendoscopy Transsphenoidal approach Anatomical parameters Nasal complications Therapeutic effects

SCI

English

First

2019 young and middle-aged elite scientific research and cultivation project of Shenzhen People's Hospital[SYKYPY201922]

Science & Technology - Other Topics ; Radiology, Nuclear Medicine & Medical Imaging

Multidisciplinary Sciences ; Radiology, Nuclear Medicine & Medical Imaging

WOS:001070971000001

ELSEVIER

Web of Science

1.Southern Med Univ, Nanfang Hosp, Dept Neurosurg, Guangzhou 510515, Peoples R China
2.Southern Med Univ, Nanfang Hosp, Dept Otolaryngol, Guangzhou 510515, Peoples R China
3.Southern Univ Sci & Technol, Affiliated Hosp 1, Jinan Univ, Dept Neurosurg,Clin Med Coll 2,Shenzhen Peoples Ho, Shenzhen 518020, Peoples R China
4.Guangdong Engn Technol Res Ctr Nervous Anat & Rela, Shenzhen 518020, Peoples R China

Wang, Hao,Hao, Wenwen,Peng, Yuping,et al. Comparasion of the anatomic and therapeutic effect of two transsphenoidal approaches under neuroendoscopy[J]. JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES,2023,16(4).

Wang, Hao.,Hao, Wenwen.,Peng, Yuping.,Qi, Songtao.,Shi, Jin.,...&Li, Yu.(2023).Comparasion of the anatomic and therapeutic effect of two transsphenoidal approaches under neuroendoscopy.JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES,16(4).

Wang, Hao,et al."Comparasion of the anatomic and therapeutic effect of two transsphenoidal approaches under neuroendoscopy".JOURNAL OF RADIATION RESEARCH AND APPLIED SCIENCES 16.4(2023).