中文版 | English
Title

Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms

Author
Corresponding AuthorZhong, Yixiu; Wang, Qi; Zhang, Jianglin
Publication Years
2023-09-12
DOI
Source Title
EISSN
1664-042X
Volume14
Abstract
Exosomes, ranging from 40 to 160 nm in diameter, are extracellular lipid bilayer microvesicles that regulate the body's physiological and pathological processes and are secreted by cells that contain proteins, nucleic acids, amino acids and other metabolites. Previous studies suggested that mesenchymal stem cell (MSC)-derived exosomes could either suppress or support keloid and hypertrophic scar progression. Although previous research has identified the potential value of MSC-exosomes in keloid and hypertrophic scar, a comprehensive analysis of different sources of MSC-exosome in keloid and hypertrophic scar is still lacking. This review mainly discusses different insights regarding the roles of MSC-exosomes in keloid and hypertrophic scar treatment and summarizes possible underlying mechanisms.
Keywords
URL[Source Record]
Indexed By
Language
English
SUSTech Authorship
First ; Corresponding
Funding Project
This work was supported by the National Natural Science Foundation of China (82073019, 82073018, and 82202851), Shenzhen Science and Technology Innovation Commission, China (Natural Science Foundation of Shenzhen), (JCYJ20210324113001005, JCYJ2021032411421["82073019","82073018","82202851"] ; National Natural Science Foundation of China["JCYJ20210324113001005","JCYJ20210324114212035","JCYJ20220530151817038"]
WOS Research Area
Physiology
WOS Subject
Physiology
WOS Accession No
WOS:001070515500001
Publisher
Data Source
Web of Science
Citation statistics
Cited Times [WOS]:0
Document TypeJournal Article
Identifierhttp://kc.sustech.edu.cn/handle/2SGJ60CL/571862
DepartmentShenzhen People's Hospital
Affiliation
1.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Dermatol,Clin Med Coll 2, Shenzhen, Guangdong, Peoples R China
2.Southern Med Univ, Nanfang Hosp, Dept Dermatol, Guangzhou, Peoples R China
3.Southern Med Univ, Dermatol Hosp, Dept Dermatol, Guangzhou, Peoples R China
4.Southern Med Univ, Nanfang Hosp, Dept Dermatol & Venereol, Guangzhou, Peoples R China
5.Cent South Univ, Xiangya Hosp, Dept Dermatol, Changsha, Hunan, Peoples R China
First Author AffilicationShenzhen People's Hospital
Corresponding Author AffilicationShenzhen People's Hospital
First Author's First AffilicationShenzhen People's Hospital
Recommended Citation
GB/T 7714
Zhong, Yixiu,Zhang, Youfan,Yu, Aijiao,et al. Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms[J]. FRONTIERS IN PHYSIOLOGY,2023,14.
APA
Zhong, Yixiu.,Zhang, Youfan.,Yu, Aijiao.,Zhang, Zhiwen.,Deng, Zhenjun.,...&Zhang, Jianglin.(2023).Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms.FRONTIERS IN PHYSIOLOGY,14.
MLA
Zhong, Yixiu,et al."Therapeutic role of exosomes and conditioned medium in keloid and hypertrophic scar and possible mechanisms".FRONTIERS IN PHYSIOLOGY 14(2023).
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