| Title | Photoacoustic micro-viscoelastography for mapping mechanocellular properties |
| Author | |
| Corresponding Author | Chen, Zhongjiang |
| Publication Years | 2023-10-01
|
| DOI | |
| Source Title | |
| ISSN | 1864-063X
|
| EISSN | 1864-0648
|
| Abstract | Cellular biomechanical properties provide essential insights into biological functions regarding health and disease. Current measurements of the biomechanical properties of cells require physical contact with cells or pre-loading on the cells. Here, we have developed photoacoustic micro-viscoelastography (PAMVE), which utilizes the phase characteristics of photoacoustic (PA) response, for mapping mechanocellular properties in a load-free manner. PAMVE realizes the local viscoelasticity measurement on the macrophages and red blood cells with micrometer scale. Furthermore, PAMVE can successfully identify the adipose cell and skeletal muscle cell due to the difference in their composition-related biomechanical properties. PAMVE represents an irreplaceable option for interrogating characteristic mechanocellular properties, opening the possibility of studying cellular mechanobiology and pathophysiology. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | First
|
| Funding Project | This study was supported by the National Natural Science Foundation of China (61705068, 62275116), Guangdong Science and Technology Department (2022A1515011984), the Natural Science Foundation of Fujian Province (2021J01813), Fujian Medical University Rese["61705068","62275116"]
; National Natural Science Foundation of China[2022A1515011984]
; Guangdong Science and Technology Department[2021J01813]
; Natural Science Foundation of Fujian Province[XRCZX2021004]
; Fujian Medical University Research Foundation of Talented Scholars[2022M721483]
|
| WOS Research Area | Biochemistry & Molecular Biology
; Biophysics
; Optics
|
| WOS Subject | Biochemical Research Methods
; Biophysics
; Optics
|
| WOS Accession No | WOS:001082115100001
|
| Publisher | |
| Data Source | Web of Science
|
| Citation statistics | |
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/582976 |
| Department | Department of Biomedical Engineering |
| Affiliation | 1.Southern Univ Sci & Technol, Dept Biomed Engn, Guangdong Prov Key Lab Adv Biomat, Shenzhen, Guangdong, Peoples R China 2.South China Normal Univ, Coll Biophoton, MOE Key Lab Laser Life Sci, Guangzhou, Peoples R China 3.South China Normal Univ, Inst Laser Life Sci, Coll Biophoton, Guangzhou, Peoples R China 4.Fujian Med Univ, Sch Med Technol & Engn, Fuzhou 350004, Peoples R China |
| First Author Affilication | Department of Biomedical Engineering |
| First Author's First Affilication | Department of Biomedical Engineering |
| Recommended Citation GB/T 7714 |
Yang, Fen,Chen, Wei,Chen, Zhongjiang. Photoacoustic micro-viscoelastography for mapping mechanocellular properties[J]. JOURNAL OF BIOPHOTONICS,2023.
|
| APA |
Yang, Fen,Chen, Wei,&Chen, Zhongjiang.(2023).Photoacoustic micro-viscoelastography for mapping mechanocellular properties.JOURNAL OF BIOPHOTONICS.
|
| MLA |
Yang, Fen,et al."Photoacoustic micro-viscoelastography for mapping mechanocellular properties".JOURNAL OF BIOPHOTONICS (2023).
|
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