| Title | Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells |
| Author | |
| Corresponding Author | Gao, Junfeng; Guo, Hong |
| Publication Years | 2023-05-01
|
| DOI | |
| Source Title | |
| ISSN | 2158-5849
|
| EISSN | 2158-5857
|
| Volume | 13Issue:5 |
| Abstract | Stomach cancer (SC) is a relatively common cancer in my country, with a high mortality rate, which seriously threatens our health. This article studied the effect of Green walnut husks (GWH) extract on the biological IP: 203.8.109.20 On: Wed, 12 Jul 2023 07:01 29 behaviors and NF-KB protein levels of gastric cancer MGC80-3 cells, and provided evidence and support for Copyright: American Scientific Pub shers the research and treatment of gastric cancer. Cell proliferation was measured by Thiazole blue and apoptosis Delivered by Ingenta by flow cytometry. Cell migration was analyzed by scratch experiment and the levels of NF-KB, NF-KBp65 and COX-2 in MGC80-3 cells were examined by Western blot and QRC-PCR. It was found that GWH extract inhib-ited cell proliferation and increased apoptosis. GWH extract significantly downregulated NF-KB, NF-KBp65 and COX-2. The growth process of cancer cells is related to biological behaviors such as cell proliferation and apoptosis. By inhibiting the biological behavior of cancer cells, inhibitory proteins can effectively inhibit gastric cancer. In summary, GWH extract has a great influence on gastric cancer MGC80-3 cells and the NF-KB protein expression. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | Corresponding
|
| WOS Research Area | Science & Technology - Other Topics
; Materials Science
|
| WOS Subject | Nanoscience & Nanotechnology
; Materials Science, Multidisciplinary
|
| WOS Accession No | WOS:001030641900002
|
| Publisher | |
| Data Source | Web of Science
|
| Citation statistics | |
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/583052 |
| Affiliation | 1.Huludao Cent Hosp, Tumor Day Ward, Huludao 125000, Liaoning, Peoples R China 2.Southern Univ Sci, Technol Yantian Hosp, Dept Emergency, Shenzhen 518000, Guangdong, Peoples R China 3.Strateg Support Force Med Ctr, Dept Med, Beijing 100000, Peoples R China 4.Steel Grp Gen Hosp, Dept Gen Surg, Anshan 114000, Liaoning, Peoples R China 5.Southern Univ Sci & Technol, Yantian Hosp, Dept Lab Med, Shenzhen 518000, Guangdong, Peoples R China |
| Corresponding Author Affilication | Southern University of Science and Technology |
| Recommended Citation GB/T 7714 |
Li, Jing,Wang, Weiguang,Li, Baowei,et al. Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells[J]. MATERIALS EXPRESS,2023,13(5).
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| APA |
Li, Jing,Wang, Weiguang,Li, Baowei,Wu, Guogang,Gao, Junfeng,&Guo, Hong.(2023).Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells.MATERIALS EXPRESS,13(5).
|
| MLA |
Li, Jing,et al."Biological behavior of the extract of green walnut husks on gastric cancer MGC80-3 cells".MATERIALS EXPRESS 13.5(2023).
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