Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China

Chen, HuaiSheng1; Chen, Ronglin2; Wu, Xinghui3; Qian, Jing4; Shi, Xuezhi3; Wan, Lulu5; Ag, Wang Fanfan4; Tong, Huasheng3

2023-06-26

10.12659/MSM.939118

MEDICAL SCIENCE MONITOR   Impact Factor & Quartile

1643-3750

Background: Coma has been considered as a valuable symptom of heatstroke. This study aimed to evaluate the role of the Glasgow Coma Scale (GCS) as an indicator of prognosis of patients with heatstroke.Material/Methods: From Jan 1st, 2013 to Dec 31st, 2020, the clinical courses of 257 heatstroke patients from 3 medical centers in Guangdong, China, were observed. Diagnosis of heatstroke was made according to Expert Consensus in China. GCSs were calculated on the 1st, 3rd, and 5th days after admission to intensive care units (ICUs). GCS <_8, as a coma criterion, was employed to predict the outcomes.Results: Seventy-five patients (29.18%) were comatose at admission. Twenty-seven (10.50%) patients, including 24 (24/75, 32.00%) coma patients and 3 (3/182,1.65%) non-coma patients died during ICU stay (P<0.0001). Patients with GCS <_8 had a 2-fold higher risk of death as compared with those with GCS >8. The area under curves (AUCs) of GCSs on the 1st, 3rd, and 5th days to predict mortality were 0.81 (0.70-0.91), 0.91 (0.84-0.98), and 0.91 (0.82-0.99), respectively. Each additional 1 year of age, 1/min of respiratory rate (RR), and 1% of hematocrit (HCT) increased the risk of death of coma patients by 3%, 6%, and 4%, respectively (all P<_0.05). Patients with improving GCSs had lower mortality rates than non-improving patients (5.71% vs 55.00%, P<0.0001) within 5 days after admission.Conclusions: GCS <_8 at admission predicted worse outcomes in heatstroke patients, which possibly enhanced the risks of death for other factors, including age, RR, and HCT.

Glasgow Coma Scale Heat Stroke Mortality Prognosis

SCI

English

First

PLA Logistics Research Project of China[18CXZ032] ; Natural Science Foundation of Guangdong Province[2021A1515012119] ; Shenzhen Key Laboratory of Prevention and Treatment of Severe Infections[ZDSYS20200811142804014] ; Shenzhen Key Medical Discipline Construction Fund[SZXK045]

Research & Experimental Medicine

Medicine, Research & Experimental

WOS:001040459000001

INT SCIENTIFIC INFORMATION, INC

CLINICAL MEDICINE

Web of Science

1.Southern Univ Sci & Technol, Jinan Univ, Shenzhen Peoples Hosp, Affiliated Hosp 1,Clin Med Coll 2,Dept Crit Care M, Shenzhen, Guangdong, Peoples R China
2.Longgang Cent Hosp Shenzhen, Dept Crit Care Med, Shenzhen, Guangdong, Peoples R China
3.Gen Hosp Southern Theatre Command Peoples Liberat, Dept Crit Care Med, Guangzhou, Guangdong, Peoples R China
4.Gen Hosp Southern Theatre Command Peoples Liberat, Dept Emergency, Guangzhou, Guangdong, Peoples R China
5.Guangzhou Univ Chinese Med, Guangzhou, Guangdong, Peoples R China

Chen, HuaiSheng,Chen, Ronglin,Wu, Xinghui,et al. Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China[J]. MEDICAL SCIENCE MONITOR,2023,29.

Chen, HuaiSheng.,Chen, Ronglin.,Wu, Xinghui.,Qian, Jing.,Shi, Xuezhi.,...&Tong, Huasheng.(2023).Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China.MEDICAL SCIENCE MONITOR,29.

Chen, HuaiSheng,et al."Glasgow Coma Scale as an Indicator of Patient Prognosis: A Retrospective Study of 257 Patients with Heatstroke from 3 Medical Centers in Guangdong, China".MEDICAL SCIENCE MONITOR 29(2023).