| Title | Immune microenvironment and therapeutic progress of recurrent hepatocellular carcinoma after liver transplantation |
| Author | |
| Corresponding Author | Yang, Lin; Ma, Nan |
| Publication Years | 2023-02-01
|
| DOI | |
| Source Title | |
| ISSN | 1936-5233
|
| Volume | 28 |
| Abstract | HCC is a highly lethal tumor, and orthotopic liver transplantation, as one of the radical treatment methods for HCC, has opened-up a new therapeutic approach for the treatment of primary liver cancer. However, tumor recurrence after liver transplantation is the main reason that affects the long-term survival of recipients. At present, the application of ICIs has brought dawn to patients with refractory HCC. However, because of the special immune tolerance state created by long-term oral immunosuppressants in patients with HCC after liver transplantation, the current focus is how to regulate the immune balance of such patients and simultaneously maximize the anti-tumor effect. This article reviews the relationship between liver cancer and immunity, im-mune tolerance of liver transplantation, immune microenvironment after liver transplantation for HCC, and the application of immunotherapy in the recurrence of liver transplantation for HCC. |
| Keywords | |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| SUSTech Authorship | First
; Corresponding
|
| Funding Project | null[SZXK079]
|
| WOS Research Area | Oncology
|
| WOS Subject | Oncology
|
| WOS Accession No | WOS:000911260300001
|
| Publisher | |
| Data Source | Web of Science
|
| Citation statistics | |
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/583150 |
| Department | The Third People's Hospital of Shenzhen 南方科技大学第一附属医院 |
| Affiliation | 1.Southern Univ Sci & Technol, Shenzhen Peoples Hosp 3, Div Liver Surg, Natl Clin Res Ctr Infect Dis,Affiliated Hosp 2, 29 Bulan Rd, Shenzhen 518112, Guangdong, Peoples R China 2.Southern Univ Sci & Technol, Shenzhen Peoples Hosp 3, Organ Transplantat Ctr, Natl Clin Res Ctr Infect Dis,Affiliated Hosp 2, 29 Bulan Rd, Shenzhen 518112, Guangdong, Peoples R China 3.Chinese Acad Med Sci & Peking Union Med Coll, Natl Clin Res Ctr Canc, Natl Canc Ctr, Dept Med Oncol,Canc Hosp, 17 Panjiayuan Nanli, Beijing 100021, Peoples R China |
| First Author Affilication | The Third People's Hospital of Shenzhen; Shenzhen People's Hospital |
| Corresponding Author Affilication | The Third People's Hospital of Shenzhen; Shenzhen People's Hospital |
| First Author's First Affilication | The Third People's Hospital of Shenzhen; Shenzhen People's Hospital |
| Recommended Citation GB/T 7714 |
Jin, Xin,Ma, Xiaoting,Zhao, Dong,et al. Immune microenvironment and therapeutic progress of recurrent hepatocellular carcinoma after liver transplantation[J]. TRANSLATIONAL ONCOLOGY,2023,28.
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| APA |
Jin, Xin,Ma, Xiaoting,Zhao, Dong,Yang, Lin,&Ma, Nan.(2023).Immune microenvironment and therapeutic progress of recurrent hepatocellular carcinoma after liver transplantation.TRANSLATIONAL ONCOLOGY,28.
|
| MLA |
Jin, Xin,et al."Immune microenvironment and therapeutic progress of recurrent hepatocellular carcinoma after liver transplantation".TRANSLATIONAL ONCOLOGY 28(2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
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