| Title | Noncancerous disease-targeting AIEgens |
| Author | |
| Corresponding Author | Duo, Yanhong; Luo, Guanghong; Yoon, Juyoung; Tang, Ben Zhong |
| Publication Years | 2023-02-06
|
| DOI | |
| Source Title | |
| ISSN | 0306-0012
|
| EISSN | 1460-4744
|
| Volume | 52Issue:3 |
| Abstract | Noncancerous diseases include a wide plethora of medical conditions beyond cancer and are a major cause of mortality around the world. Despite progresses in clinical research, many puzzles about these diseases remain unanswered, and new therapies are continuously being sought. The evolution of bio-nanomedicine has enabled huge advancements in biosensing, diagnosis, bioimaging, and therapeutics. The recent development of aggregation-induced emission luminogens (AIEgens) has provided an impetus to the field of molecular bionanomaterials. Following aggregation, AIEgens show strong emission, overcoming the problems associated with the aggregation-caused quenching (ACQ) effect. They also have other unique properties, including low background interferences, high signal-to-noise ratios, photostability, and excellent biocompatibility, along with activatable aggregation-enhanced theranostic effects, which help them achieve excellent therapeutic effects as an one-for-all multimodal theranostic platform. This review provides a comprehensive overview of the overall progresses in AIEgen-based nanoplatforms for the detection, diagnosis, bioimaging, and bioimaging-guided treatment of noncancerous diseases. In addition, it details future perspectives and the potential clinical applications of these AIEgens in noncancerous diseases are also proposed. This review hopes to motivate further interest in this topic and promote ideation for the further exploration of more advanced AIEgens in a broad range of biomedical and clinical applications in patients with noncancerous diseases. |
| URL | [Source Record] |
| Indexed By | |
| Language | English
|
| Important Publications | ESI Highly Cited Papers
|
| SUSTech Authorship | First
; Corresponding
|
| Funding Project | null[82102904]
; null[JCYJ20190807144605514]
; null[JCYJ20210324113405014]
; null[JCYJ20190808154213097]
; null[2021R1A6A1A10039823]
|
| WOS Research Area | Chemistry
|
| WOS Subject | Chemistry, Multidisciplinary
|
| WOS Accession No | WOS:000907711700001
|
| Publisher | |
| ESI Research Field | CHEMISTRY
|
| Data Source | Web of Science
|
| Citation statistics |
Cited Times [WOS]:16
|
| Document Type | Journal Article |
| Identifier | http://kc.sustech.edu.cn/handle/2SGJ60CL/583160 |
| Department | Shenzhen People's Hospital |
| Affiliation | 1.Jinan Univ, Southern Univ Sci & Technol, Shenzhen Peoples Hosp, Affiliated Hosp 1,Dept Radiat Oncol,Clin Med Col, Shenzhen 518020, Guangdong, Peoples R China 2.Karolinska Inst, Dept Microbiol, Tumor & Cell Biol MTC, Stockholm, Sweden 3.Dalian Univ Technol, Sch Chem Engn, Dept Pharmacol, State Key Lab Fine Chem, Dalian, Peoples R China 4.Ewha Womans Univ, Dept Chem & Nanosci, 52 Ewhayeodae Gil, Seoul 03760, South Korea 5.Chinese Univ Hong Kong, Shenzhen Inst Aggregate Sci & Technol, Sch Sci & Engn, Shenzhen 518172, Guangdong, Peoples R China 6.Sun Yat Sen Univ, Affiliated Hosp 8, Dept Orthoped, Shenzhen 518033, Guangdong, Peoples R China 7.Chinese Univ Hong Kong, Sch Med, Life & Hlth Sci, Shenzhen 518172, Guangdong, Peoples R China |
| First Author Affilication | Shenzhen People's Hospital |
| Corresponding Author Affilication | Shenzhen People's Hospital |
| First Author's First Affilication | Shenzhen People's Hospital |
| Recommended Citation GB/T 7714 |
Duo, Yanhong,Luo, Guanghong,Zhang, Wentao,et al. Noncancerous disease-targeting AIEgens[J]. CHEMICAL SOCIETY REVIEWS,2023,52(3).
|
| APA |
Duo, Yanhong.,Luo, Guanghong.,Zhang, Wentao.,Wang, Renzhi.,Xiao, Gary Guishan.,...&Tang, Ben Zhong.(2023).Noncancerous disease-targeting AIEgens.CHEMICAL SOCIETY REVIEWS,52(3).
|
| MLA |
Duo, Yanhong,et al."Noncancerous disease-targeting AIEgens".CHEMICAL SOCIETY REVIEWS 52.3(2023).
|
| Files in This Item: | There are no files associated with this item. | |||||
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